microRNAs and Neurodegenerative Diseases.

  title={microRNAs and Neurodegenerative Diseases.},
  author={Lifeng Qiu and Eng King Tan and Li Zeng},
  journal={Advances in experimental medicine and biology},
microRNAs (miRNAs) are small, noncoding RNA molecules that through imperfect base-pairing with complementary sequences of target mRNA molecules, typically cleave target mRNA, causing subsequent degradation or translation inhibition. Although an increasing number of studies have identified misregulated miRNAs in the neurodegenerative diseases (NDDs) Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis, which suggests that alterations in the miRNA… CONTINUE READING
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