microRNA target predictions in animals

  title={microRNA target predictions in animals},
  author={N. Rajewsky},
  journal={Nature Genetics},
  volume={38 Suppl 1},
  • N. Rajewsky
  • Published 2006
  • Biology, Medicine
  • Nature Genetics
  • In recent years, microRNAs (miRNAs) have emerged as a major class of regulatory genes, present in most metazoans and important for a diverse range of biological functions. Because experimental identification of miRNA targets is difficult, there has been an explosion of computational target predictions. Although the initial round of predictions resulted in very diverse results, subsequent computational and experimental analyses suggested that at least a certain class of conserved miRNA targets… CONTINUE READING

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    Publications referenced by this paper.
    MicroRNAs Genomics, Biogenesis, Mechanism, and Function
    • 28,196
    • PDF
    Combinatorial microRNA target predictions
    • 4,335
    • PDF
    Human MicroRNA Targets
    • 3,227
    • PDF
    Silencing of microRNAs in vivo with ‘antagomirs’
    • 3,551
    • PDF
    Principles of MicroRNA–Target Recognition
    • 2,153