microRNA target predictions in animals

@article{Rajewsky2006microRNATP,
  title={microRNA target predictions in animals},
  author={N. Rajewsky},
  journal={Nature Genetics},
  year={2006},
  volume={38 Suppl 1},
  pages={S8-S13}
}
  • N. Rajewsky
  • Published 2006
  • Biology, Medicine
  • Nature Genetics
  • In recent years, microRNAs (miRNAs) have emerged as a major class of regulatory genes, present in most metazoans and important for a diverse range of biological functions. Because experimental identification of miRNA targets is difficult, there has been an explosion of computational target predictions. Although the initial round of predictions resulted in very diverse results, subsequent computational and experimental analyses suggested that at least a certain class of conserved miRNA targets… CONTINUE READING

    Figures, Tables, and Topics from this paper.

    Explore Further: Topics Discussed in This Paper

    Paper Mentions

    OBSERVATIONAL CLINICAL TRIAL
    The primary purpose of this study is to test new methods to diagnose BE in time before it turns into advanced cancer. Once BE is diagnosed, the current standard of care is to monitor… Expand
    ConditionsBarrett's Esophagus, Esophageal Adenocarcinoma, Gastroesophageal Reflux
    A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing
    • 3,262
    • PDF
    A Pattern-Based Method for the Identification of MicroRNA Binding Sites and Their Corresponding Heteroduplexes
    • 1,622
    • PDF
    Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP
    • 2,302
    • PDF
    MicroRNA signatures in human cancers
    • 6,498
    • PDF
    miRWalk - Database: Prediction of possible miRNA binding sites by "walking" the genes of three genomes
    • 1,349
    • PDF
    Dysregulation of Cardiogenesis, Cardiac Conduction, and Cell Cycle in Mice Lacking miRNA-1-2
    • 1,315
    • Highly Influenced
    • PDF

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 52 REFERENCES
    MicroRNAs Genomics, Biogenesis, Mechanism, and Function
    • 28,196
    • PDF
    Combinatorial microRNA target predictions
    • 4,335
    • PDF
    Human MicroRNA Targets
    • 3,227
    • PDF
    Silencing of microRNAs in vivo with ‘antagomirs’
    • 3,551
    • PDF
    Principles of MicroRNA–Target Recognition
    • 2,153