microRNA expression alteration after arsenic trioxide treatment in HepG-2 cells.

  title={microRNA expression alteration after arsenic trioxide treatment in HepG-2 cells.},
  author={Xian-zhi Meng and Tong-sen Zheng and Xi Chen and Jia-bei Wang and Weihui Zhang and Shang-ha Pan and HongChi Jiang and Lian-xin Liu},
  journal={Journal of gastroenterology and hepatology},
  volume={26 1},
BACKGROUND AND AIM More and more microRNA (miRNA) are found to be involved in tumor genesis and progress. Arsenic trioxide has been an effective chemotherapeutic drug in cancer therapy for many years. In this study, we aimed to find the miRNA involved in the mechanisms of arsenic trioxide treatment in cancer therapy. METHODS We detected the expression profile of miRNA by miRNA microarray and quantitative real-time polymerase chain reaction. Cell viability assay, flow cytometry analysis… CONTINUE READING
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