microRNA-497 inhibits invasion and metastasis of colorectal cancer cells by targeting vascular endothelial growth factor-A.

Abstract

OBJECTIVES microRNAs (miRNAs), are non-coding RNAs that regulate gene expression, and are involved in tumour development. The aim of this study was to investigate microRNA-497 (miR-497) expression and its role in development of colorectal cancer (CRC). MATERIALS AND METHODS RT-PCR was performed to detect expression of miR-497 in CRC cell lines (HCT8, LOVO… (More)
DOI: 10.1111/cpr.12237

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