microRNA-33 Regulates Macrophage Autophagy in Atherosclerosis.

Abstract

OBJECTIVE Defective autophagy in macrophages leads to pathological processes that contribute to atherosclerosis, including impaired cholesterol metabolism and defective efferocytosis. Autophagy promotes the degradation of cytoplasmic components in lysosomes and plays a key role in the catabolism of stored lipids to maintain cellular homeostasis. microRNA-33… (More)
DOI: 10.1161/ATVBAHA.116.308916

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