microRNA-21 modulates cell proliferation and sensitivity to doxorubicin in bladder cancer cells.

Abstract

Transitional cell carcinomas (TCCs) of the urinary bladder are common malignancies with a high recurrence rate. Since microRNA-21 (miR-21) may contribute to tumorigenesis and chemoresistance in many cancer types, we aimed to investigate its efficacy in TCCs. The expression of miR-21 and its target PTEN was determined by real-time qRT-PCR and western… (More)
DOI: 10.3892/or.2011.1245

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