microRNA-1/133a and microRNA-206/133b clusters: Dysregulation and functional roles in human cancers

@inproceedings{Nohata2012microRNA1133aAM,
  title={microRNA-1/133a and microRNA-206/133b clusters: Dysregulation and functional roles in human cancers},
  author={Nijiro Nohata and Toyoyuki Hanazawa and Hideki Enokida and Naohiko Seki},
  booktitle={Oncotarget},
  year={2012}
}
MicroRNAs (miRNAs) are endogenous short non-coding RNA molecules that regulate gene expression by repressing translation or cleaving RNA transcripts in a sequence-specific manner. A growing body of evidence suggests that miRNAs are aberrantly expressed in many human cancers and that they play significant roles in the initiation, development and metastasis of human cancers. Genome-wide miRNA expression signatures provide information on the aberrant expression of miRNAs in cancers rapidly and… CONTINUE READING
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