microDuMIP: target-enrichment technique for microarray-based duplex molecular inversion probes

@inproceedings{Yoon2015microDuMIPTT,
  title={microDuMIP: target-enrichment technique for microarray-based duplex molecular inversion probes},
  author={Jung-ki Yoon and Jinwoo Ahn and Han Sang Kim and Soo Min Han and Hoon Jang and Min Goo Lee and Ji Hyun Lee and Duhee Bang},
  booktitle={Nucleic acids research},
  year={2015}
}
Molecular inversion probe (MIP)-based capture is a scalable and effective target-enrichment technology that can use synthetic single-stranded oligonucleotides as probes. Unlike the straightforward use of synthetic oligonucleotides for low-throughput target capture, high-throughput MIP capture has required laborious protocols to generate thousands of single-stranded probes from DNA microarray because of multiple enzymatic steps, gel purifications and extensive PCR amplifications. Here, we… CONTINUE READING
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