miRTRAP, a computational method for the systematic identification of miRNAs from high throughput sequencing data

@inproceedings{Hendrix2009miRTRAPAC,
  title={miRTRAP, a computational method for the systematic identification of miRNAs from high throughput sequencing data},
  author={David A Hendrix and Michael Levine and Weiyang Shi},
  booktitle={Genome Biology},
  year={2009}
}
MicroRNAs (miRs) have been broadly implicated in animal development and disease. We developed a novel computational strategy for the systematic, whole-genome identification of miRs from high throughput sequencing information. This method, miRTRAP, incorporates the mechanisms of miR biogenesis and includes additional criteria regarding the prevalence and quality of small RNAs arising from the antisense strand and neighboring loci. This program was applied to the simple chordate Ciona… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.
43 Citations
49 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 43 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 49 references

Similar Papers

Loading similar papers…