miRNA studies in in vitro and in vivo activated hepatic stellate cells.

@article{Maubach2011miRNASI,
  title={miRNA studies in in vitro and in vivo activated hepatic stellate cells.},
  author={Gunter Maubach and Michelle Chin Chia Lim and Jinmiao Chen and Henry Yang and Lang Zhuo},
  journal={World journal of gastroenterology},
  year={2011},
  volume={17 22},
  pages={2748-73}
}
AIM To understand which and how different miRNAs are implicated in the process of hepatic stellate cell (HSC) activation. METHODS We used microarrays to examine the differential expression of miRNAs during in vitro activation of primary HSCs (pHSCs). The transcriptome changes upon stable transfection of rno-miR-146a into an HSC cell line were studied using cDNA microarrays. Selected differentially regulated miRNAs were investigated by quantitative real-time polymerase chain reaction during in… CONTINUE READING
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