miRNA profiling for clear cell renal cell carcinoma: biomarker discovery and identification of potential controls and consequences of miRNA dysregulation.

@article{White2011miRNAPF,
  title={miRNA profiling for clear cell renal cell carcinoma: biomarker discovery and identification of potential controls and consequences of miRNA dysregulation.},
  author={Nicole M White and Tian Tian Bao and J{\"o}rg Grigull and Youssef M. Youssef and Andrew H. A. Girgis and Maria Diamandis and Eman Fatoohi and Maged Metias and Richardson John D'Arcy Honey and Robert S Stewart and Kenneth T Pace and G A Georg Bjarnason and George Makram Yousef},
  journal={The Journal of urology},
  year={2011},
  volume={186 3},
  pages={1077-83}
}
PURPOSE Renal cell carcinoma is the most common neoplasm of the adult kidney. Currently to our knowledge there are no biomarkers for diagnostic, prognostic or predictive applications for renal cell carcinoma. miRNAs are nonprotein coding RNAs that negatively regulate gene expression and are potential biomarkers for cancer. MATERIALS AND METHODS We analyzed 70 matched pairs of clear cell renal cell carcinoma and normal kidney tissues from the same patients by microarray analysis and validated… CONTINUE READING
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