miRNA-mRNA Correlation-Network Modules in Human Prostate Cancer and the Differences between Primary and Metastatic Tumor Subtypes

@inproceedings{Zhang2012miRNAmRNACM,
  title={miRNA-mRNA Correlation-Network Modules in Human Prostate Cancer and the Differences between Primary and Metastatic Tumor Subtypes},
  author={Wensheng Zhang and Andrea Edwards and Wei Fan and Erik K. Flemington and Kun Qiu Zhang},
  booktitle={PloS one},
  year={2012}
}
Recent studies have shown the contribution of miRNAs to cancer pathogenesis. Prostate cancer is the most commonly diagnosed cancer in men. Unlike other major types of cancer, no single gene has been identified as being mutated in the majority of prostate tumors. This implies that the expression profiling of genes, including the non-coding miRNAs, may substantially vary across individual cases of this cancer. The within-class variability makes it possible to reconstruct or infer disease-specific… CONTINUE READING
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