miRNA biomarkers in cyst fluid augment the diagnosis and management of pancreatic cysts.

@article{Matthaei2012miRNABI,
  title={miRNA biomarkers in cyst fluid augment the diagnosis and management of pancreatic cysts.},
  author={Hanno Matthaei and Dennis Wylie and Maura B. Lloyd and Marco dal Molin and Jon Kemppainen and Skye C. Mayo and Christopher L. Wolfgang and Richard David Schulick and Laura Langfield and Bernard F. Andruss and Alex Tamas Adai and Ralph H. Hruban and Anna E. Szafranska-Schwarzbach and Anirban Maitra},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2012},
  volume={18 17},
  pages={
          4713-24
        }
}
PURPOSE The diagnosis of pancreatic cystic lesions has increased dramatically. Most are benign, whereas some, such as intraductal papillary mucinous neoplasms (IPMN), represent precursors of pancreatic adenocarcinoma. Therapeutic stratification of IPMNs is challenging without precise information on dysplasia grade and presence of invasion. We assessed the diagnostic benefit of using miRNAs as biomarkers in pancreatic cyst fluid, focusing on IPMNs because of their frequency and malignant… CONTINUE READING

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