miRNA-491-5p and GIT1 serve as modulators and biomarkers for oral squamous cell carcinoma invasion and metastasis.

@article{Huang2014miRNA4915pAG,
  title={miRNA-491-5p and GIT1 serve as modulators and biomarkers for oral squamous cell carcinoma invasion and metastasis.},
  author={Wei-Chieh Huang and Shih-Hsuan Chan and T. Jang and Jer-Wei Chang and Y. Ko and T. Yen and Shang-Lun Chiang and W. Chiang and T. Shieh and C. Liao and J. Juang and Hsueh-Chun Wang and A. Cheng and Y. Lu and Luhai Wang},
  journal={Cancer research},
  year={2014},
  volume={74 3},
  pages={
          751-64
        }
}
MicroRNAs offer tools to identify and treat invasive cancers. Using highly invasive isogenic oral squamous cell carcinoma (OSCC) cells, established using in vitro and in vivo selection protocols from poorly invasive parental cell populations, we used microarray expression analysis to identify a relative and specific decrease in miR-491-5p in invasive cells. Lower expression of miR-491-5p correlated with poor overall survival of patients with OSCCs. miR-491-5p overexpression in invasive OSCC… Expand
miR-491-5p suppresses cell growth and invasion by targeting Notch3 in nasopharyngeal carcinoma.
MiRNA-491-5p inhibits cell proliferation, invasion and migration via targeting JMJD2B and serves as a potential biomarker in gastric cancer.
miR-149-5p inhibits cell proliferation and invasion through targeting GIT1 in medullary thyroid carcinoma
MicroRNA-491-5p suppresses cervical cancer cell growth by targeting hTERT.
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References

SHOWING 1-10 OF 69 REFERENCES
MicroRNA‐138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF‐1α
Oncogenic Function and Early Detection Potential of miRNA-10b in Oral Cancer as Identified by microRNA Profiling
Identification of MMP-9 specific microRNA expression profile as potential targets of anti-invasion therapy in glioblastoma multiforme
Human beta-defensin-3 (hBD-3) upregulated by LPS via epidermal growth factor receptor (EGFR) signaling pathways to enhance lymphatic invasion of oral squamous cell carcinoma.
  • Yu Shuyi, W. Feng, +6 authors Yang Hongyu
  • Biology, Medicine
  • Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • 2011
Talin1 promotes tumor invasion and metastasis via focal adhesion signaling and anoikis resistance.
Cardiotoxin III suppresses MDA-MB-231 cell metastasis through the inhibition of EGF/EGFR-mediated signaling pathway.
Current trends in miRNAs and their relationship with oral squamous cell carcinoma.
  • M. Pérez-Sayáns, G. Pilar, +4 authors A. García-García
  • Medicine, Biology
  • Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • 2012
MMP2 role in breast cancer brain metastasis development and its regulation by TIMP2 and ERK1/2
The non-coding 3' UTR of CD44 induces metastasis by regulating extracellular matrix functions.
...
1
2
3
4
5
...