miRNA-29b suppresses prostate cancer metastasis by regulating epithelial-mesenchymal transition signaling.

@article{Ru2012miRNA29bSP,
  title={miRNA-29b suppresses prostate cancer metastasis by regulating epithelial-mesenchymal transition signaling.},
  author={Peng Ru and Robert David Steele and Philip Newhall and Nancy J. Phillips and K{\'a}roly T{\'o}th and Ratna B Ray},
  journal={Molecular cancer therapeutics},
  year={2012},
  volume={11 5},
  pages={1166-73}
}
Prostate cancer remains the second leading cause of cancer deaths among American men. Early diagnosis increases survival rate in patients; however, treatments for advanced disease are limited to hormone ablation techniques and palliative care. Thus, new methods of treatment are necessary for inhibiting prostate cancer disease progression. Here, we have shown that miRNA-29b (miR-29b) expression was lower in prostate cancer cells (PC3 and LNCaP) as compared with immortalized prostate epithelial… CONTINUE READING
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