miRNA-223 promotes gastric cancer invasion and metastasis by targeting tumor suppressor EPB41L3.

@article{Li2011miRNA223PG,
  title={miRNA-223 promotes gastric cancer invasion and metastasis by targeting tumor suppressor EPB41L3.},
  author={Xiaohua Li and Ying Zhang and Hongwei Zhang and Xiaonan Liu and Taiqian Gong and Mengbin Li and Li Jian Sun and Gang Ji and Yongquan Shi and Zheyi Han and Shuang Han and Yongzhang Nie and Xiong Chen and Qinchuan Zhao and Jie Ding and Kaichun Wu and Fan Daiming},
  journal={Molecular cancer research : MCR},
  year={2011},
  volume={9 7},
  pages={824-33}
}
Traditional research modes aim to find cancer-specific single therapeutic target. Recently, emerging evidence suggested that some micro-RNAs (miRNA) can function as oncogenes or tumor suppressors. miRNAs are single-stranded, small noncoding RNA genes that can regulate hundreds of downstream target genes. In this study, we evaluated the miRNA expression patterns in gastric carcinoma and the specific role of miR-223 in gastric cancer metastasis. miRNA expression signature was first analyzed by… CONTINUE READING