miR526b and miR655 Induce Oxidative Stress in Breast Cancer

@article{Shin2019miR526bAM,
  title={miR526b and miR655 Induce Oxidative Stress in Breast Cancer},
  author={Bonita Shin and Riley Feser and Braydon Nault and Stephanie Hunter and Sujit Maiti and Kingsley Chukwunonso Ugwuagbo and Mousumi Majumder},
  journal={International Journal of Molecular Sciences},
  year={2019},
  volume={20}
}
In eukaryotes, overproduction of reactive oxygen species (ROS) causes oxidative stress, which contributes to chronic inflammation and cancer. MicroRNAs (miRNAs) are small, endogenously produced RNAs that play a major role in cancer progression. We established that overexpression of miR526b/miR655 promotes aggressive breast cancer phenotypes. Here, we investigated the roles of miR526b/miR655 in oxidative stress in breast cancer using in vitro and in silico assays. miRNA-overexpression in MCF7… Expand
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