miR126 positively regulates mast cell proliferation and cytokine production through suppressing Spred1.

Abstract

The protein known as Spred1 (Sprouty-related Ena/VASP homology-1 domain-containing protein) has been identified as a negative regulator of growth factor-induced ERK/mitogen-activated protein kinase activation. Spred1 has also been implicated as the target of microRNA-126 (miR126), a miRNA located within the Egfl7 gene, and is involved in the regulation of… (More)
DOI: 10.1111/j.1365-2443.2011.01529.x

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Cite this paper

@article{Ishizaki2011miR126PR, title={miR126 positively regulates mast cell proliferation and cytokine production through suppressing Spred1.}, author={Takuma Ishizaki and Taiga Tamiya and Koji Taniguchi and Rimpei Morita and Reiko Kato and Fuyuki Okamoto and Kazuko Saeki and Masatoshi Nomura and Yoshihisa Nojima and Akihiko Yoshimura}, journal={Genes to cells : devoted to molecular & cellular mechanisms}, year={2011}, volume={16 7}, pages={803-14} }