miR126-5p repression of ALCAM and SetD5 in endothelial cells regulates leucocyte adhesion and transmigration.

@article{Poissonnier2014miR1265pRO,
  title={miR126-5p repression of ALCAM and SetD5 in endothelial cells regulates leucocyte adhesion and transmigration.},
  author={Lo{\"i}c Poissonnier and Ga{\"e}lle Villain and Fabrice Soncin and Virginie Mattot},
  journal={Cardiovascular research},
  year={2014},
  volume={102 3},
  pages={
          436-47
        }
}
AIMS miR126-5p is processed from the miR126-3p/-5p duplex, which is expressed in endothelial cells and gives rise to the guide strand miR126-3p and the passenger strand miR126-5p. miR126-3p has prominent roles in vascular development and diseases, whereas the expression and physiological functions of miR126-5p are unknown. The purpose of this study was to evaluate the expression and role of miR126-5p in blood vessel endothelial cells. METHODS AND RESULTS miR126-5p is mostly expressed in blood… CONTINUE READING

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