miR-93 Promotes Cell Proliferation in Gliomas through Activation of PI3K/Akt Signaling Pathway

@inproceedings{Jiang2015miR93PC,
  title={miR-93 Promotes Cell Proliferation in Gliomas through Activation of PI3K/Akt Signaling Pathway},
  author={Lili Jiang and Chanjuan Wang and Fangyong Lei and Longjuan Zhang and Xin Zhang and Aibin Liu and Geyan Wu and Jinrong Zhu and Libing Song},
  booktitle={Oncotarget},
  year={2015}
}
The PI3K/Akt signaling pathway is frequently activated in various human cancer types and plays essential roles in development and progression of cancers. Multiple regulators, such as phosphatase and tensin homolog (PTEN) and PH domain leucine rich repeat protein phosphatases (PHLPP), have also found to be involved in suppression of the PI3K/Akt signaling pathway. However, how suppressive effects mediated by these regulators are concomitantly disrupted in cancers, which display constitutively… CONTINUE READING
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