miR-450b-5p induced by oncogenic KRAS is required for colorectal cancer progression

Abstract

The development and progression of CRC are regarded as a complicated network and progressive event including genetic and/or epigenetic alterations. Recent researches revealed that MicroRNAs are biomarkers and regulators of CRC progression. Analyses of published microarray datasets revealed that miR-450b-5p was highly up-regulated in CRC tissues. In addition… (More)
DOI: 10.18632/oncotarget.11016

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