miR-449a promotes liver cancer cell apoptosis by downregulation of Calpain 6 and POU2F1

Abstract

Our previous study shows that Calpain 6 (CAPN6) expression is regulated by PI3K-Akt in liver cancer through POU2F1 and CAPN6 which promote cell proliferation and inhibit apoptosis of liver cancer cells. microRNAs (miRNAs) plays important roles in regulation of gene expression. However, whether miRNAs regulates CAPN6 expression and its cellular function is… (More)
DOI: 10.18632/oncotarget.4821

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