miR-34c attenuates epithelial-mesenchymal transition and kidney fibrosis with ureteral obstruction

Abstract

micro RNAs (miRNAs) are small non-coding RNAs that act as posttranscriptional repressors by binding to the 3'-UTR of target mRNAs. On the other hand, mesenchymal-epithelial transition (EMT) and kidney fibrosis is a pathological process of chronic kidney disease (CKD), and its relationship to miRNAs is becoming recognized as a potential target for CKD… (More)
DOI: 10.1038/srep04578

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