miR-25 promotes gastric cancer cells growth and motility by targeting RECK

  title={miR-25 promotes gastric cancer cells growth and motility by targeting RECK},
  author={Hongying Zhao and Yu Wang and Liu Yang and Rongke Jiang and Wenqing Li},
  journal={Molecular and Cellular Biochemistry},
Gastric cancer (GC) is the second leading cause of cancer-related death worldwide. Recently, accumulating evidence suggests that microRNAs (miRNAs) play prominent roles in tumorigenesis and metastasis. Here, we confirmed that miR-25 was significantly increased in human GC tissues and cell lines. Forced expression of miR-25 remarkably enhanced cell proliferation, migration, and invasion in GC cells, whereas inhibition of miR-25 by inhibitor caused significant suppression of proliferation and… CONTINUE READING
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Up-regulation of miR-182 by beta-catenin in breast cancer increases tumorigenicity and invasiveness by targeting the matrix metalloproteinase inhibitor RECK

  • CH Chiang, MF Hou
  • Biochim Biophys Acta 4:3067–3076
  • 2013
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