miR-23a downregulation modulates the inflammatory response by targeting ATG12-mediated autophagy

@inproceedings{Si2018miR23aDM,
  title={miR-23a downregulation modulates the inflammatory response by targeting ATG12-mediated autophagy},
  author={Xiang Si and Daiyin Cao and Juan Chen and Yao Nie and Zhiyi Jiang and Min-ying Chen and Jian-Feng Wu and Xiang-dong Guan},
  booktitle={Molecular medicine reports},
  year={2018}
}
Autophagy, part of the innate immune defense mechanisms, is activated during the initial phase of septic insult. Previous studies indicated that micro (mi)RNAs are additionally involved in the host response to sepsis; however, the association between miRNAs and autophagy during this process is not fully understood. To study the role of miRNA (miR)‑23a in… CONTINUE READING