miR-221 and miR-222 expression increased the growth and tumorigenesis of oral carcinoma cells.

@article{Yang2011miR221AM,
  title={miR-221 and miR-222 expression increased the growth and tumorigenesis of oral carcinoma cells.},
  author={Chun-Ju Yang and Wilma Grace Shen and Chung-Ji Liu and Yun-Wen Chen and H Lu and Meng-Miao Tsai and Shu-Chun Lin},
  journal={Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology},
  year={2011},
  volume={40 7},
  pages={560-6}
}
BACKGROUNDS MicroRNAs are small noncoding RNAs involved in posttranscriptional gene regulation, which play an important role in both physiological functioning and pathological progression. The miR-221/miR-222 microRNA family has been shown to be related to the neoplastic process in a number of different types of cancers; nevertheless, its function in oral squamous cell carcinoma (OSCC) remained uncertain. MATERIALS AND METHODS Paired OSCC and matched noncancerous oral mucosa were examined for… CONTINUE READING