miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer.

@article{Kondo2008miR206EI,
  title={miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer.},
  author={Naoto Kondo and Tatsuya Toyama and Hiroshi Sugiura and Yoshitaka Fujii and Hiroko Yamashita},
  journal={Cancer research},
  year={2008},
  volume={68 13},
  pages={5004-8}
}
Expression levels of estrogen receptor (ER) alpha govern estrogen-dependent growth, response to endocrine therapy, and prognosis in ERalpha-positive breast cancer. Multiple mechanisms involved in altering ERalpha gene expression in breast cancer have been identified, including ERalpha gene amplification as well as transcriptional silencing by DNA methylation of CpG islands within the ERalpha promoter and mutations within the open reading frame of ERalpha. However, expression levels of ERalpha… CONTINUE READING
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