miR-205 promotes the growth, metastasis and chemoresistance of NSCLC cells by targeting PTEN.

@article{Lei2013miR205PT,
  title={miR-205 promotes the growth, metastasis and chemoresistance of NSCLC cells by targeting PTEN.},
  author={Lin Lei and Yaping Huang and Wenrong Gong},
  journal={Oncology reports},
  year={2013},
  volume={30 6},
  pages={2897-902}
}
Non-small cell lung cancer (NSCLC) is one of the most common causes of cancer-related mortality worldwide. microRNAs (miRNAs) play critical roles in carcinogenesis. miR-205 has been shown to be upregulated in NSCLC. In the present study, we identified the promotive effects of miR-205 on various significant biological properties of NSCLC cells, and confirmed the regulation of PTEN by miR-205. The expression of miR-205 was examined by quantitative real-time PCR both in NSCLC cell lines and… CONTINUE READING
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