miR-205 negatively regulates the androgen receptor and is associated with adverse outcome of prostate cancer patients

@inproceedings{Hagman2013miR205NR,
  title={miR-205 negatively regulates the androgen receptor and is associated with adverse outcome of prostate cancer patients},
  author={Zandra Hagman and Benedikta S. Haflidad{\'o}ttir and Jens Adam Ceder and Olivia Larne and Anders Bjartell and Harri Lilja and Anders Edsj{\"o} and Yvonne Ceder},
  booktitle={British Journal of Cancer},
  year={2013}
}
Background:The microRNA-205 (miR-205) has been shown to be deregulated in prostate cancer (PCa). Here we continue to investigate the prognostic and therapeutic potential of this microRNA.Methods:The expression of miR-205 is measured by qRT–PCR and in situ hybridisation in a well-documented PCa cohort. An AGO2-based RIP-Chip assay is used to identify targets that are verified with western blots, luciferase reporter assay, ELISA and immunohistochemistry.Results:The expression of miR-205 is… CONTINUE READING

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