miR-200a-5p regulates myocardial necroptosis induced by Se deficiency via targeting RNF11

@inproceedings{Yang2018miR200a5pRM,
  title={miR-200a-5p regulates myocardial necroptosis induced by Se deficiency via targeting RNF11},
  author={Tianshu Yang and Changyu Cao and Jie Yang and Tianqi Liu and Xin Gen Lei and Ziwei Zhang and Shiwen Xu},
  booktitle={Redox biology},
  year={2018}
}
Necroptosis has been discovered as a new paradigm of cell death and may play a key role in heart disease and selenium (Se) deficiency. Hence, we detected the specific microRNA (miRNA) in response to Se-deficient heart using microRNAome analysis. For high-throughput sequencing using Se-deficient chicken cardiac tissue, we selected miR-200a-5p and its target gene ring finger protein 11 (RNF11) based on differential expression in cardiac tissue and confirmed the relationship between miR-200a-5p… CONTINUE READING
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