miR-200a-5p regulates myocardial necroptosis induced by Se deficiency via targeting RNF11

@article{Yang2018miR200a5pRM,
  title={miR-200a-5p regulates myocardial necroptosis induced by Se deficiency via targeting RNF11},
  author={T. Yang and Changyu Cao and J. Yang and T. Liu and X. Lei and Z. Zhang and Shiwen Xu},
  journal={Redox Biology},
  year={2018},
  volume={15},
  pages={159 - 169}
}
  • T. Yang, Changyu Cao, +4 authors Shiwen Xu
  • Published 2018
  • Medicine, Biology
  • Redox Biology
  • Necroptosis has been discovered as a new paradigm of cell death and may play a key role in heart disease and selenium (Se) deficiency. Hence, we detected the specific microRNA (miRNA) in response to Se-deficient heart using microRNAome analysis. For high-throughput sequencing using Se-deficient chicken cardiac tissue, we selected miR-200a-5p and its target gene ring finger protein 11 (RNF11) based on differential expression in cardiac tissue and confirmed the relationship between miR-200a-5p… CONTINUE READING

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 63 REFERENCES
    miR-874 regulates myocardial necrosis by targeting caspase-8
    • 75
    • PDF
    A miR-19 regulon that controls NF-κB signaling
    • 127
    • PDF
    RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
    • 1,308
    RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome
    • 113
    • PDF