miR-195 in human primary mesenchymal stromal/stem cells regulates proliferation, osteogenesis and paracrine effect on angiogenesis

@inproceedings{Almeida2016miR195IH,
  title={miR-195 in human primary mesenchymal stromal/stem cells regulates proliferation, osteogenesis and paracrine effect on angiogenesis},
  author={Maria In{\^e}s Almeida and Andreia M Silva and Daniel Marques Vasconcelos and Catarina R Almeida and Hugo R Caires and Marta Teixeira Pinto and George A. Calin and Susana Gomes Santos and Mario A. Barbosa},
  booktitle={Oncotarget},
  year={2016}
}
Mesenchymal Stromal/Stem Cells (MSC) are currently being explored in diverse clinical applications, including regenerative therapies. Their contribution to regeneration of bone fractures is dependent on their capacity to proliferate, undergo osteogenesis and induce angiogenesis. This study aimed to uncover microRNAs capable of concomitantly regulate these mechanisms. Following microRNA array results, we identified miR-195 and miR-497 as downregulated in human primary MSC under osteogenic… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 27 CITATIONS

MicroRNAs and Fracture Healing

  • Calcified Tissue International
  • 2017
VIEW 8 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Decrease of miR-195 Promotes Chondrocytes Proliferation and Maintenance of Chondrogenic Phenotype via Targeting FGF-18 Pathway

  • International journal of molecular sciences
  • 2017
VIEW 3 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

MICROmanagement of Runx2 Function in Skeletal Cells

  • Current Molecular Biology Reports
  • 2019
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 47 REFERENCES

MiR-497∼195 cluster microRNAs regulate osteoblast differentiation by targeting BMP signaling.

  • Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
  • 2015
VIEW 1 EXCERPT