miR-194 targets RBX1 gene to modulate proliferation and migration of gastric cancer cells

@article{Chen2014miR194TR,
  title={miR-194 targets RBX1 gene to modulate proliferation and migration of gastric cancer cells},
  author={Xiaonan Chen and Yuanyuan Wang and Wenqiao Zang and Yuwen Du and Min Li and Guoqiang Zhao},
  journal={Tumor Biology},
  year={2014},
  volume={36},
  pages={2393-2401}
}
RING box protein1 (RBX1), an essential component of SCF E3 ubiquitin ligases, plays an important role in gastric cancer. In the study, miR-194 and RBX1 expression was evaluated in 76 pairs of gastric tumor and non-tumor tissue samples by qRT-PCR, and clinicopathological characteristics were analyzed. CCK8, transwell assay, wound healing assay, and flow cytometry assay were performed to evaluate the effect of miR-194 on gastric cancer (GC) cellular proliferation, invasion, migration, apoptosis… CONTINUE READING
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