miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging

  title={miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging},
  author={Matthias J. Hackl and Stefan Brunner and Klaus Fortschegger and Carina Schreiner and Lucia Micutkova and Christoph Mueck and Gerhard Thomas Laschober and G{\"u}nter Lepperdinger and Natalie Sampson and Peter Berger and Dietmar Herndler-Brandstetter and Matthias Wieser and Harald K{\"u}hnel and Alois Strasser and Mark Rinnerthaler and Michael Breitenbach and Michael Mildner and Leopold Eckhart and Erwin Tschachler and Andrea Trost and Johann W. Bauer and Christine Papak and Zlatko Trajanoski and Marcel Scheideler and Regina Grillari-Voglauer and Beatrix Grubeck-Loebenstein and Pidder Jansen-Duerr and Johannes Grillari},
  booktitle={Aging cell},
Aging is a multifactorial process where deterioration of body functions is driven by stochastic damage while counteracted by distinct genetically encoded repair systems. To better understand the genetic component of aging, many studies have addressed the gene and protein expression profiles of various aging model systems engaging different organisms from yeast to human. The recently identified small non-coding miRNAs are potent post-transcriptional regulators that can modify the expression of… CONTINUE READING