miR-155 targets Caspase-3 mRNA in activated macrophages.

@article{Santis2016miR155TC,
  title={miR-155 targets Caspase-3 mRNA in activated macrophages.},
  author={Rebecca De Santis and Anke Liepelt and Jana C. Mossanen and Anne Dueck and Nadine Simons and Antje Mohs and Christian Trautwein and Gunter Meister and Gernot Marx and Antje Ostareck-Lederer and Dirk H. Ostareck},
  journal={RNA biology},
  year={2016},
  volume={13 1},
  pages={
          43-58
        }
}
To secure the functionality of activated macrophages in the innate immune response, efficient life span control is required. Recognition of bacterial lipopolysaccharides (LPS) by toll-like receptor 4 (TLR4) induces downstream signaling pathways, which merge to induce the expression of cytokine genes and anti-apoptotic genes. MicroRNAs (miRNAs) have emerged as important inflammatory response modulators, but information about their functional impact on apoptosis is scarce. To identify miRNAs… CONTINUE READING
BETA
1
Twitter Mention

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

MicroRNA-155 Promotes Myocardial Infarction-Induced Apoptosis by Targeting RNA-Binding Protein QKI

  • Oxidative medicine and cellular longevity
  • 2019
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 61 REFERENCES

Noncoding RNAs, cytokines, and inflammation-related diseases.

  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 2015

Translation control of TAK1 mRNA by hnRNP K modulates LPS-induced macrophage activation

A Liepelt, JC Mossanen, +6 authors A. Ostareck-Lederer
  • RNA
  • 2014

Similar Papers

Loading similar papers…