miR-149 promotes epithelial-mesenchymal transition and invasion in nasopharyngeal carcinoma cells.

@article{Luo2011miR149PE,
  title={miR-149 promotes epithelial-mesenchymal transition and invasion in nasopharyngeal carcinoma cells.},
  author={Zhaohui Luo and Liyang Zhang and Zheng Li and Chen Jiang and Yafei Dai and Xiaoping Liu and Ying Zheng and Haibo Yu and Juanjuan Xiang and Guiyuan Li},
  journal={Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences},
  year={2011},
  volume={36 7},
  pages={604-9}
}
OBJECTIVE To investigate the function and mechanism of miR-149 in nasopharyngeal carcinoma (NPC). METHODS The expression of miR-149 was examined by real-time PCR and calculated by 2(-▵▵Ct) method. The cell proliferation was analyzed by MTT assay. The cell migration and invasion were shown by the wound healing assay and transwell migration assay, and the expression of E-cadherin was detected by Western blot. RESULTS The expression of miR-149 was higher in NPC cell lines 5-8F and 6-10B than… CONTINUE READING
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