Corpus ID: 44294379

miR-148b functions as a tumor suppressor in non-small cell lung cancer by targeting carcinoembryonic antigen (CEA).

@article{Liu2014miR148bFA,
  title={miR-148b functions as a tumor suppressor in non-small cell lung cancer by targeting carcinoembryonic antigen (CEA).},
  author={Guo-long Liu and Xia Liu and Xiao-bin Lv and Xiaopai Wang and Xi-Sheng Fang and Yi Sang},
  journal={International journal of clinical and experimental medicine},
  year={2014},
  volume={7 8},
  pages={
          1990-9
        }
}
  • Guo-long Liu, Xia Liu, +3 authors Yi Sang
  • Published in
    International journal of…
    2014
  • Medicine
  • Aberrant expression of miR-148b has been found in several types of cancer, but its expression and potential biologic role in non-small cell lung cancer (NSCLC) are still largely unknown. Here, we found that miR-148b was commonly under-expressed in human non-small celllung cancer (NSCLC) specimens and cell lines. The overexpression of miR-148b dramatically suppressed NSCLC cell proliferation and migration. Furthermore, miR-148b could regulate carcinoembryonic antigen (CEA) expression by… CONTINUE READING

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