miR-148a downregulates the expression of transforming growth factor-β2 and SMAD2 in gastric cancer.

@article{Zhang2016miR148aDT,
  title={miR-148a downregulates the expression of transforming growth factor-β2 and SMAD2 in gastric cancer.},
  author={Wei Zhang and Yan Li},
  journal={International journal of oncology},
  year={2016},
  volume={48 5},
  pages={1877-85}
}
The effects of miR-148a in regulating the expression of TGFβ2 and SMAD2 in MNNG-initiated gastric cancer rats and the mechanism of action in GC cells were determined. Effects of miR-148a on the proliferation, migration, and invasion of GC cell lines were demonstrated. We used Wistar rats, Balb/c nude mice, and GC cell lines. Rats were treated with MNNG to… CONTINUE READING