miR-138 suppresses cell proliferation and invasion by inhibiting SOX9 in hepatocellular carcinoma.

@article{Liu2016miR138SC,
  title={miR-138 suppresses cell proliferation and invasion by inhibiting SOX9 in hepatocellular carcinoma.},
  author={Yahui Liu and Wei Zhang and Kai Liu and Songyang Liu and Bai Ji and Ying-chao Wang},
  journal={American journal of translational research},
  year={2016},
  volume={8 5},
  pages={2159-68}
}
Accumulating evidence suggests that miR-138 expression was frequently downregulated in different cancer types and involves in the progression of tumorigenesis. However, the biological role and molecular mechanism of miR-138 involvement in hepatocellular carcinoma (HCC) still remains largely unknown. Therefore, in the present study, we investigated the role of miR-138 in the progression of HCC. We found that miR-138 expression levels were significantly downregulated in HCC tissues and cell lines… CONTINUE READING

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