miR-129-3p, as a diagnostic and prognostic biomarker for renal cell carcinoma, attenuates cell migration and invasion via downregulating multiple metastasis-related genes

@article{Chen2014miR1293pAA,
  title={miR-129-3p, as a diagnostic and prognostic biomarker for renal cell carcinoma, attenuates cell migration and invasion via downregulating multiple metastasis-related genes},
  author={Xuanyu Chen and Anming Ruan and Xuegang Wang and Weiwei Han and Rong Wang and Ning Lou and Hailong Ruan and Bin Qiu and Hongmei Yang and Xiaoping Zhang},
  journal={Journal of Cancer Research and Clinical Oncology},
  year={2014},
  volume={140},
  pages={1295-1304}
}
Downregulation of miRNA expression has been identified as a novel feature of renal cell carcinoma (RCC). Recently, miR-129-2 is well known to be frequently reduced by DNA methylation and has anti-tumor effects in various tumors but so far not in RCC. The aim of this study was to investigate the clinical significance and the role of it in RCC. The expression levels of miR-129-3p and miR-129-5p, two mature products of miR-129-2, were determined by real-time quantitative reverse transcription PCR… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 54 references

epigenetic regulation of miR-34b and miR-129 expression in gastric cancer

  • KW tsai, CW Wu, +8 authors WC lin
  • Int J Cancer 129(11):2600–2610
  • 2011
Highly Influential
4 Excerpts

Methylation - mediated repression of microRna 1292 enhances oncogenic sOX 4 expression in hCC

  • X Chen, Zhang l, +8 authors F lu
  • liver Int
  • 2013
Highly Influential
4 Excerpts

quent Dna methylation of MiR1292 and its potential clinical implication in hepatocellular carcinoma

  • CY lu, KY lin, tien Mt, Wu Ct, Uen Yh, tseng tl
  • genes Chromosomes Cancer
  • 2013
Highly Influential
4 Excerpts

epigenetic repression of microRna1292 leads to overexpression of sOX 4 oncogene in endometrial cancer

  • YW huang, JC liu, +5 authors huang th
  • Cancer Res
  • 2009
Highly Influential
7 Excerpts

Similar Papers

Loading similar papers…