miR-125b inhibited epithelial–mesenchymal transition of triple-negative breast cancer by targeting MAP2K7

@inproceedings{Hong2016miR125bIE,
  title={miR-125b inhibited epithelial–mesenchymal transition of triple-negative breast cancer by targeting MAP2K7},
  author={Liquan Hong and Feng Pan and Huifen Jiang and Lahong Zhang and Yuhua Liu and Chengsong Cai and Chunzhen Hua and Xian Hai Luo and Jinhua Sun and Zhaojun Chen},
  booktitle={OncoTargets and therapy},
  year={2016}
}
MicroRNAs (miRNAs) play important roles in diverse biological processes and are emerging as key regulators of tumorigenesis and tumor progression. Among the differentially expressed miRNAs in breast cancer, miR-125b was revealed to be deregulated and associated with poor prognosis and chemoresistance in triple-negative breast cancer (TNBC), but the mechanism is still unknown. In our study, we showed downregulated expression of miR-125b in TNBC tissues and decreased migration and invasion in miR… CONTINUE READING

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