miR-1254 and miR-574-5p: serum-based microRNA biomarkers for early-stage non-small cell lung cancer.

@article{Foss2011miR1254AM,
  title={miR-1254 and miR-574-5p: serum-based microRNA biomarkers for early-stage non-small cell lung cancer.},
  author={Kristen M Foss and Chao Sima and Donatella Ugolini and Monica Neri and Kristi E Allen and Glen J. Weiss},
  journal={Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer},
  year={2011},
  volume={6 3},
  pages={482-8}
}
INTRODUCTION The ability to diagnose non-small cell lung cancer (NSCLC) at an early stage may lead to improved survival. The aim of this study was to identify differentially expressed serum-based microRNAs (miRNAs) between patients with early-stage NSCLC and controls. These miRNAs may serve as biomarkers for NSCLC early detection. METHODS miRNA profiling was performed on total RNA extracted from serum obtained from 22 individuals (11 controls and 11 patients with early-stage NSCLC… CONTINUE READING
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