miR-10a inhibits dendritic cell activation and Th1/Th17 cell immune responses in IBD

@article{Wu2014miR10aID,
  title={miR-10a inhibits dendritic cell activation and Th1/Th17 cell immune responses in IBD},
  author={Wei Wu and C. He and Changqin Liu and Anthony T. Cao and Xiaochang Xue and H. Evans-Marin and Mingming Sun and Leilei Fang and Suxia Yao and I. Pinchuk and D. Powell and Zhanju Liu and Y. Cong},
  journal={Gut},
  year={2014},
  volume={64},
  pages={1755 - 1764}
}
Objective Although both innate and adaptive responses to microbiota have been implicated in the pathogenesis of IBD, it is still largely unknown how they are regulated during intestinal inflammation. In this report, we investigated the role of microRNA (miR)-10a, a small, non-coding RNA, in the regulation of innate and adaptive responses to microbiota in IBD. Methods miR-10a expression was analysed in the inflamed mucosa of IBD patients treated with or without antitumour necrosis factor (anti… Expand
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