miR-10a Regulates Proliferation of Human Cardiomyocyte Progenitor Cells by Targeting GATA6

@inproceedings{Liang2014miR10aRP,
  title={miR-10a Regulates Proliferation of Human Cardiomyocyte Progenitor Cells by Targeting GATA6},
  author={Dandan Liang and Lixiao Zhen and Tianyou Yuan and Jian Huang and Fangfei Deng and Wuyahan and Hong Zhang and Lei Pan and Yiqing Liu and Erlinda The and Zuoren Yu and Weidong Zhu and Yuzhen Zhang and Li Li and Luying Peng and Jun Li and Yihan Chen},
  booktitle={PloS one},
  year={2014}
}
microRNAs (miRNAs) play essential roles in cardiogenesis. The altered expression of miRNAs can result in cardiac malformations by inducing abnormalities in the behavior of cardiac cells. However, the role of miR-10a in the regulation of cardiomyocyte progenitor cells (CMPCs) remains undetermined. In the present study, we found that up- or down-regulation of miR-10a inhibited or promoted the proliferation of human CMPCs, respectively, without affecting their differentiation toward cardiomyocytes… CONTINUE READING
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