mefE is necessary for the erythromycin-resistant M phenotype in Streptococcus pneumoniae.

@article{TaitKamradt1997mefEIN,
  title={mefE is necessary for the erythromycin-resistant M phenotype in Streptococcus pneumoniae.},
  author={Amelia G Tait-Kamradt and Joanna Clancy and Melissa T Cronan and Fadia Dib-Hajj and Lillian M Wondrack and Wen Yuan and Joyce Sutcliffe},
  journal={Antimicrobial agents and chemotherapy},
  year={1997},
  volume={41 10},
  pages={2251-5}
}
Recently, it was shown that a significant number of erythromycin-resistant Streptococcus pneumoniae and Streptococcus pyogenes strains contain a determinant that mediates resistance via a putative efflux pump. The gene encoding the erythromycin-resistant determinant was cloned and sequenced from three strains of S. pneumoniae bearing the M phenotype (macrolide resistant but clindamycin and streptogramin B susceptible). The DNA sequences of mefE were nearly identical, with only 2-nucleotide… CONTINUE READING
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