mTORC1 signaling and the metabolic control of cell growth.

@article{BenSahra2017mTORC1SA,
  title={mTORC1 signaling and the metabolic control of cell growth.},
  author={Issam Ben-Sahra and Brendan D. Manning},
  journal={Current opinion in cell biology},
  year={2017},
  volume={45},
  pages={72-82}
}
mTOR [mechanistic target of rapamycin] is a serine/threonine protein kinase that, as part of mTORC1 (mTOR complex 1), acts as an important molecular connection between nutrient signals and the metabolic processes indispensable for cell growth. While there has been pronounced interest in the upstream mechanisms regulating mTORC1, the full range of downstream… CONTINUE READING

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