mTORC 1 Signaling - Activated Increases in Muscle Protein Synthesis induced by leucine and Phosphatidic Acid : A Brief Review

Abstract

The mammalian target of rapamycin (mTOR) is a signaling network that functions to regulate muscle protein synthesis (MPS). The effects of leucine and phosphatidic acid (PA) availability and growth factors such as insulin and insulin-like growth factor 1 (IGF-1) can up-regulate this signaling pathway and increase the initiation of protein translation… (More)

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