mTOR limits the recruitment of CD11b+Gr1+Ly6Chigh myeloid-derived suppressor cells in protecting against murine immunological hepatic injury.

Abstract

The mTOR pathway integrates diverse environmental inputs, including immune signals and metabolic cues, to direct the innate and adaptive immune responses. MDSCs are a heterogeneous cell population that plays a crucial regulatory effect in immune-related diseases. However, whether mTOR signaling affects the functions of MDSCs remains largely unknown. Here… (More)
DOI: 10.1189/jlb.0913473

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Cite this paper

@article{Zhang2014mTORLT, title={mTOR limits the recruitment of CD11b+Gr1+Ly6Chigh myeloid-derived suppressor cells in protecting against murine immunological hepatic injury.}, author={Yan Zhang and Yujing Bi and Hui Yang and Xi Chen and Huanrong Liu and Yun Lu and Zhengguo Zhang and Jiongbo Liao and Shan Yang and Yiwei Chu and Ruifu Yang and Guang Liu}, journal={Journal of leukocyte biology}, year={2014}, volume={95 6}, pages={961-70} }