mTOR inhibitor-associated proteinuria in kidney transplant recipients.

@article{Diekmann2012mTORIP,
  title={mTOR inhibitor-associated proteinuria in kidney transplant recipients.},
  author={F. Diekmann and A. Torregrosa Andr{\'e}s and Federico Oppenheimer},
  journal={Transplantation reviews},
  year={2012},
  volume={26 1},
  pages={27-9}
}
The use of mammalian target of rapamycin inhibitor (mTOR-I) after kidney transplantation has been associated with a higher incidence of proteinuria compared with calcineurin inhibitors (CNIs). This review will focus on mTOR-I-associated proteinuria in different settings after kidney transplantation: de novo mTOR-I treatment in combination with CNI, de novo mTOR-I-containing and CNI-free treatment, early conversion from a CNI-based regimen to an mTOR-I-based regimen, and late conversion. Some… CONTINUE READING

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