mTOR as a Key Regulator in Maintaining Skeletal Muscle Mass

  title={mTOR as a Key Regulator in Maintaining Skeletal Muscle Mass},
  author={Mee-Sup Yoon},
  journal={Frontiers in Physiology},
  • Mee-Sup Yoon
  • Published 2017
  • Biology, Medicine
  • Frontiers in Physiology
  • Maintenance of skeletal muscle mass is regulated by the balance between anabolic and catabolic processes. Mammalian target of rapamycin (mTOR) is an evolutionarily conserved serine/threonine kinase, and is known to play vital roles in protein synthesis. Recent findings have continued to refine our understanding of the function of mTOR in maintaining skeletal muscle mass. mTOR controls the anabolic and catabolic signaling of skeletal muscle mass, resulting in the modulation of muscle hypertrophy… CONTINUE READING
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