mRNAs for insulin-like growth factor-II (IGF-II) and variant IGF-II are co-expressed in human fetal ovary and uterus.

@article{Yeh1991mRNAsFI,
  title={mRNAs for insulin-like growth factor-II (IGF-II) and variant IGF-II are co-expressed in human fetal ovary and uterus.},
  author={Jiunn-rong Yeh and Frank Danehy and Rapin Osathanondh and L. Villa-Komaroff},
  journal={Molecular and cellular endocrinology},
  year={1991},
  volume={80 1-3},
  pages={75-82}
}
Insulin-like growth factor-II (IGF-II) is postulated to have autocrine and/or paracrine functions in developing fetal tissues, but has never been reported in human fetal reproductive organs. The forms of IGF-II found in normal human serum include a 67 amino acid form and a variant form resulting from alternate splicing of the mRNA such that Ser-29 is… CONTINUE READING